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Button 14 512  Final List of Posters

 

Sunday, June 21st

14.30
Registration
16.30 - 17.00

Opening (Aula Magna)

Welcome addresses of the Authorities

17.00 - 17.20
Entertainment

Aula Magna

Chairs: Mary Garson, Angela Agostiano

17.30 - 18.15 PL1 - Frances Arnold
Innovation by evolution (and AI): bringing new chemistry to life
18.15 - 19.00 

Chemistry Europe Lecture

PL2 - Luisa De Cola
Supramolecular and hybrid responsive nanomaterials in/for living organism
19.00 Welcome Party
Via Festa del Perdono 7, Milano
  

Monday, June 22nd

8.30
Registration

Aula Magna

Chairs: Luigi Lay, Chuan He

9.00 - 9.45 PL3 - Peter Seeberger
Molecular Glycobiology Enabled by Automated Glycan Assembly as Basis for Vaccines, Diagnostics and Therapeutics
9.45 - 10.30 PL4 - Dan Yang
Reactive Oxygen Species: Detection, Imaging, and Translational Roles in Disease Mechanisms and Therapy
10.30 - 11.00

Coffee Break

Aula Magna

Chairs: Laura Russo, Francesca Baldelli Bombelli

11.00 - 11.30 KN1 - Lorenzo Moroni
Probing Function with Designing Structure: Instructive Scaffolds for Tissue Regeneration
11.30 - 12.00 KN2 - Francesco Stellacci
Small Molecule Stabilization of Proteins and Nanoparticles: Rethinking Colloidal Stabilization
12.00 - 12.30 KN3 - Hiroshi Abe
Chemistry-based design of mRNA to explore new functions
12.30 - 13.00 KN4 - Mikiko Sodeoka
Live Cell Imaging Using Raman Tag
13.00 - 15.00

Lunch & Poster Session

Aula 400

Chairs: Valeria D’Auria, Mikiko Sodeoka

15.00 - 15.20 IL1 - Arnaud Gautier
Illuminating and controlling cell function with chemogenetics
15.20 - 15.35 OC1 - Zhen Xi
Genome Therapy Meeting Promises for Tumor Growth Inhibition
15.35 - 15.50 OC2 - Todd Markham
Directing the chemoenzymatic assembly of desferrioxamine B

Aula 410

Chairs: Cesare Gennari, Marcella Bonchio

15.00 - 15.20 IL2 - Frédéric Taran
Bioorthogonal reactions with mesoionics, new tools for chemical biology
15.20 - 15.35 OC3 - Zhang Yan
Bioorthogonal reactions based on o-diones and their biological applications
15.35 - 15.50 OC4 - Luis Branco
Design of Oseltamivir and Hydroxychloroquine Ionic Salts for Improved Antiviral Performance
15.50 - 16.05 OC5 - Alberto Dal Corso
A Bispecific Small Molecule Mediates Armed Antibodies Targeting of Bone Mineral Matrix

Aula 431

Chairs: Barbara la Ferla, Amelia Rauter

15.00 - 15.20 IL3 - Roberto Adamo
Advancement of site selective conjugation for innovative glycoconjugate vaccine design
15.20 - 15.35 OC6 - Francesca Cadamuro
3D Bioprinted Glioblastoma Multiforme Model, Impact of Glycosignature on Cell Behaviour and Drug Response
15.35 - 15.50 OC7 - Marcos Couto
Carborane-Phenyl Bioisosteric Replacement in EGFR Inhibitors: A 3D Approach toward Anti-Glioblastoma Agents
15.50 - 16.05 OC8 - Nuno Manuel Xavier
Novel D-Glucuronamide-Based Nucleot(i)de Analogs as Anticancer and Antibacterial Hits
16.00 - 16.30

Coffee Break

Aula 400

Chairs: Giorgio Colombo, Andrea Stevenazzi

16.30 - 16.50 IL4 - Stefano Serapian
Machine Learning to Boost Detection of Allosteric Fingerprints from Molecular Dynamics
16.50 - 17.05 OC9 – Yoav Shamir
Discovery of covalent ligands with AlphaFold3
17.05 - 18.00 Workshop
Jacopo Gomena, Giorgio Carbone, Marco Zambra (Italfarmaco)
Do Neural Networks Dream of Drug-Like Molecules? An Introduction and Critical Perspective to Generative AI for Chemical Space Exploration

Aula 410

Chairs: Luis Branco, Joe Barchi

16.30 - 16.45 OC10 - Maria Cristina De Rosa
Optimization of a Xanthine-Based Senolytic Lead Compound Targeting HSP90α
16.45 - 17.00 OC11 - Doralyn Dalisay
Multitarget β-Secretase and Cholinesterase Inhibition by Phenolic Amides from Philippine Single-Origin Artisan Chocolate Revealed by Metabolomics, Enzyme Assays, and Docking
17.00 - 17.15 OC12 - Luigi Menduti
Very Fast Gelating Injectable Gelatin Hydrogels obtained via Cytochrome C Mediated Radical Polymerization
17.15 - 17.30 OC13 - Smriti Mukherjee
Mimicking Collagen Fibrils through Hyperstable and Short Collagen-Mimetic Peptide Assemblies
17.30 - 17.45 OC14 - Marco Piazzoni
3D bioprinted hydrogel model to study glycosignature evolution in pancreatic adenocarcinoma (PDAC) after x-ray treatment

Aula 431

Chairs: Arnaud Gautier, Roberto Corradini

16.30 - 17.00 KN5 - Francesco Ricci
Programmable and responsive DNA-based synthetic cells, reactions and structures
17.00 - 17.30 KN6 - Nicolas Winssinger
Programming responsive assemblies from PNA-encoded and folded peptides
17.30 - 17.50 IL5 - Daniela Montesarchio
Exploring multivalency effects in G4-forming aptamers for diagnostics and theranostics

Tuesday, June 23rd

8.30
Registration

Aula 400

Chairs: Daniela Arosio, Young-Tae Chang

9.00 - 9.30 KN7 - Anna Maria Papini
Bioorganic Chemistry in Peptide Science: From Proof-of-Concept to Applications in Diagnostics, Therapeutics, and Cosmeceuticals
9.30 - 9.50 IL6 - Paolo Arosio
Engineering Enzymatic Reactions and Protein Aggregation by Biomolecular Condensates
9.50 - 10.05 OC15 - Jeella Acedo
Characterization of a Novel Antimicrobial Peptide Discovered through Genome Mining
10.05 - 10.20 OC16 - Kelly Bugatti
From Extraction to Immunoreactivity: A Chemical‑Biology View of C‑Phycocyanin from Arthrospira platensis

Aula 410

Chairs: Giovanni Appendino, Motonari Uesugi

9.00 - 9.30 KN8 - Marcella Bonchio
Supramolecular Quantasomes for Artificial Photosynthesis
9.30 - 9.50 IL7 - Lena Barra
Enzyme and Natural Product Discovery in Non-Canonical Pathways
9.50 - 10.05 OC17 - Stefano Fedeli
Lipopeptide nanozymes as biocompatible and membrane-safe catalysts for intracellular bioorthogonal reactions
10.05 - 10.20 OC18 - Saad Zekri
Identification of Novel Sulfonamide-Based Inhibitors of MMP-2 Using Ligand-Based Pharmacophore Approaches
10.20 - 10.35 OC19 - Virinder Parmar
Green and sustainable “biocatalytic” synthesis of polymeric electrolytes for Na-ion batteries

Aula 431

Chairs: Federica Compostella, Marco Guerrini

9.00 - 9.30 KN9 - Francesco Sansone
Calixarenes, versatile and inspiring tools at the service of and protagonist in bioorganic chemistry
9.30 - 9.50 IL8 - Srinivas Hotha
Chemical Glycan Editing Tools
9.50 - 10.05 OC20 - Jérôme Désiré
N-sulfonyl azalevoglucosan, a versatile platform for the diversity-oriented synthesis of polysubstituted piperidines
10.05 - 10.20 OC21 - Chiara Mangini
Synthesis of Novel 1,2-benziothiazine-fused Galactose Mimetics via inverse electron demand Hetero-Diels-Alder Reaction as Selective Galectin-1 ligands
10.20 - 10.35 OC22 - Sarah Mazzotta
Site-Selective Editing of Monosaccharides: Access to New C-5 Modified Chemotypes
10.35 - 11.00

Coffee Break

Aula 400

Chairs: Jose Garcia-Fernandez, Srinivas Hotha

11.00 - 11.30 KN10 - Vito Ferro
Site-selective photobromination of carbohydrates
11.30 - 11.50 IL9 - Laurence Mulard
From a unique tetrasaccharide scaffold to a broad serotype coverage Shigella flexneri vaccine candidate
11.50 - 12.10 IL10 - Joe Barchi
Design and Development of Immunotherapies for Pancreatic Cancer based on Mucin Glycopeptides
12.10 - 12.30 IL11 - Linda Del Bino
Proof of concept for a single-dose group B Streptococcus vaccine based on capsular polysaccharide conjugated to Qβ virus-like particle
12.30 - 12.45 OC23 - Giuseppe D’Orazio
Harnessing Commensal Lipid Architecture: Toward Immunomodulatory glycolipids inspired by Bacteroides fragilis Lipid A
12.45 - 13.00 OC24 - Jacopo Tricomi
Engineering glyconanomaterials for the fine regulation of the immune response

Aula 410

Chairs: Francesco Stellacci, Sara Sattin

11.00 - 11.30 KN11 - Kate Jolliffe
Sensors for biologically important phosphates: from pyrophosphate to phospholipids
11.30 - 11.50 IL12 - Jun-Seok Lee
Illuminating Drug–Target Interactions in Metabolic Disease through Photo-Crosslinking Chemoproteomics
11.50 - 12.10 IL13 - Takeaki Ozawa
Opto-bioanalysis: Imaging and controlling GPCR activities in live cells
12.10 - 12.30 OC25 - Giuseppina Raffaini
DNA as Drug Carrier: a Hydrophobic β-Cyclodextrin Channel in a Supramolecular Structure by Molecular Dynamics study
12.30 - 12.45 OC26 - Iva Poshkuleva
Impact of phosphate position in the biocatalytic self-assembly of short carbohydrate amphiphiles
12.45 - 13.00 OC27 - Zhu Jiyu
Imaging Intracellular Membrane Dynamics with Conjugated Oligoelectrolytes

Aula 431

Chairs: Zhen Xi, Paolo Arosio

11.10 - 11.30 IL14 - Mark Robillard
Click-to-Release for on-target activation and off-target deactivation
11.30 - 11.50 IL15 - Daniela Arosio
PD-L1 ligand Ir(III) complex conjugates as dual action anticancer agents
11.50 - 12.10 OC28 - Motonari Uesugi
Live-Cell Monitoring of Liquid–Solid Transitions of Biomolecular Condensates
12.10 - 12.30 OC29 - Andrea Sartori
Antifibrotic Efficacy of a Nintedanib−Peptide Conjugate Targeting αVβ6 Integrin in IPF
12.30 - 12.45 OC30 - Giulia Cazzaniga
Translating drug conjugate strategies to crop protection: glycoside hydrolase-cleavable linkers for controlled agrodrug release
12.45 - 13.00 OC31 - Rajesh Viswanathan
Biomimetic Synthesis of Pyrroloindoline-DKPs Unveil Pro-Apoptotic P-gP Inhibitors with Minimal Cytotoxicity
13.00 - 15.00

Lunch Break & Poster Session

Aula 400

Chairs: Daniele Passarella, Mark Robillard

15.00 - 15.30 KN12 - Annemieke Madder
Best of Both Worlds or Double-Edged Sword? Antibody-Mediated Delivery of Oligonucleotides
15.30 - 15.45 OC32 - Valeria Romanucci
Targeting neurodegeneration with novel L-Carnosine mimics: insights into metal chelation and CN1 interaction
15.45 - 16.00 OC33 - Mihaela Dascalu
TMS-substituted Schiff base with four-ring heterocyclic scaffolds and its metal complexes: synthesis, characterization, and anticancer activity

Aula 410

Chairs: Sabrina Bertini

15.00 - 15.30 KN13 - Giuseppe Melacini
Can Allostery Turn a Self-Protein into a Pathogenic Antigen?
15.30 - 15.45 OC34 - Nunzio Cardullo
Turning Biowaste to Resin: Lignin Recovery from Dried Fruit Shells and Synthesis of phenol- and formaldehyde-free bio-materials
15.45 - 16.00 OC35 - Sara Amata
Design, synthesis, and biological evaluation of 1,2,4-oxadiazole salts and their derived functional materials

Aula 431

Chairs: Laura Polito, Kate Jolliffe

15.00 - 15.30 KN14 - Twan Lammers
Smart Cancer Nanomedicine
15.30 - 15.45 OC36 - José Manuel García Fernández
Light-Controlled Nucleic Acid Delivery with Azobenzene Janus Glycosides
15.45 - 16.00 OC37 - Luis Branco
Hybrid Nanoparticle–Ionic Drug Systems as a Platform for Enhanced Therapeutics
16.00 - 16.30

Coffee Break

Aula 410

Chairs: Daniela Montesarchio, Francesco Ricci

16.30 - 17.00 KN15 - Cynthia Burrows
Ribosomal responses to cellular stressors analyzed by nanopore sequencing
17.00 - 17.20 IL16 - Roberto Corradini
Biomolecular-engineered Peptide Nucleic Acids (PNAs) as multifaceted health tools
17.20 - 17.40 IL17 - Markus Wilhelmsson
Studying RNA biology and therapeutics using fluorescent base analogues
17.40 - 17.55 OC38 - Silvia Pezzola
Kuquinones derivatives as new potent mTorc1 inhibitors

Aula 400

Chairs: Nicolas Winssinger, Shaomin Shuang

16.30 - 17.00 KN16 - Young-Tae Chang
Chemical Based Aging Research through Fluorescent Live Cell Probe
17.00 - 17.20 IL18 - Martin Schnermann
Imaging-Guided Design of Targeted Therapeutics
17.20 - 17.40 OC39 - Neda Bagheri
Topology-gated CRISPR–Cas12a platform for real-time monitoring of topoisomerase activity and drug evaluation
17.40 - 18.00 OC40 - Marta Rosati
Exploring the transition from physicochemical characteristics to the application of fluorinated Janus-type dendrimers in gene delivery

Aula 431

Chairs: Vito Ferro, Carmen Ortiz Mellet

16.30 - 17.00 KN17 - Franck Fieschi
C-type Lectin receptors at the heart of sugar-mediated immune recognition of pathogens or altered self: developments and potential applications at the chemistry/biology interface
17.00 - 17.20 IL19 - Martina Delbianco
Carbohydrate foldamers and assemblies
17.20 - 17.40 IL20 - Matthieu Sollogoub
Cyclodextrin Self-Assembly: From Virus-Like Architectures to Antiviral Systems
17.40 - 18.00 OC41 - Jonel Saludes
Beyond Sucrose: Expanding the Chemical Space of Sugarcane-Derived Natural Products through Metabolomic Profiling of Muscovado Sugar

Wednesday, June 24th

8.30
Registration

Aula Magna

Chairs: Anna Bernardi

9.00 - 9.45 PL5 - Rui Reis
Engineering Natural Origin Regenerative Medicine Platforms and 3D Disease Models Based on Those
9.45 - 10.30 PL6 - Helma Wennemers
Asymmetric Catalysis with Peptides – From Simple to Complex Environments
10.30 - 11.00

Coffee Break

Aula Magna

Chairs: Martin Schnermann, Martina Delbianco

11.00 - 11.30 KN18 - Bengang Xing
Disease Biology-driven Molecular Labeling Toolkits for Precision Theranostics
11.30 - 11.50 IL21 - Shaomin Shuang
Carbon Dots-Based Fluorescent Sensing Arrays: Rational Design for Discrimination of Food Colorants and Sulfur species
11.50 - 12.05 OC42 - Boris Vauzeilles
Chemical biology for the detection of pathogens and reactive oxygen species
12.05 - 12.20 OC43 - Peng Zou
Spatially resolved mapping of subcellular proteome with immuno proximity labeling
12.20 - 12.35 OC44 - Daniela Verga
Photoactivatable warheads for G-quadruplex photoaffinity labelling

Aula 431

Chairs: Franck Fieschi, Matthieu Sollogoub

11.00 - 11.30 KN19 - Carmen Ortiz Mellet
Glycomimetics: From Chemical Mimics to Probes and Therapeutics
11.30 - 11.50 IL22 - Xuechen Li
Protein chemical synthesis and engineering to study protein glycosylation
11.50 - 12.05 OC45 - Marcello Marelli
Glyco-Gold nanoparticles: a microfluidic approach to deploy multi-functionality
12.05 - 12.20 OC46 - Rebecca Ferrisi
Targeted Nrf2 Activation through Controlled Release of Endogenous Lipid-Derived Electrophiles from Reversible Michael Adducts
12.20 - 12.35 OC47 - Florence Mahuteau-Betzer
A Novel Bioorthogonal Fluorogenic Click-and-Release Reaction for Imaging and Controlled Drug Delivery
12.35 - 12.50 OC48 - Claudia Pigliacelli
Protease-resistant peptide vesicles as nanoscale carriers

Aula 400

Chairs: Cristina Airoldi, Giuseppe Melacini

11.00 - 11.30 KN20 - Alba Silipo
Decoding the Glycan Landscape: How Sugar Structure Shapes Function and Recognition
11.30 - 11.50 IL23 - Nicola Abrescia
Cryo EM of African Horse Sickness Virus VP2 guides vaccine engineering
11.50 - 12.05 OC49 - Cristina Di Carluccio
Molecular Insights into Sialoglycan Recognition by Siglecs
12.05 - 12.20 OC50 - Laura Ragona
Mechanistic insights into protein misfolding and aggregation processes by real-time solution NMR studies
12.20 - 12.35 OC51 - Carmela Gallo
Elucidating a dual TREM2-ligand pathway by a cellular three components FRET/FLIM system
12.35 - 12.50 OC52 - Serena Vittorio
MetabolEx: An Integrated Tool for Small‑Molecule Metabolite Generation and Metabolic Pathway Analysis
12.50 - 13.05 OC53 - Linda Molteni
Decoding myrtle activity against Alzheimer’s disease: characterization of metabolic composition and anti-amyloidogenic activity of myrtle leaves extracts
13.00 - 14.30

Lunch

Aula Magna

Chairs: Bengang Xing

14.30 - 15.00 KN21 - Gordan Lauc
Glycans as biomarkers and functional effectors of cardiometabolic diseases - insights from the first 200,000 analysed Human Glycomes
15.00 - 15.30 KN22 - Dario Neri
Tumor targeting
15.30 - 16.00

Coffee Break

Aula Magna

Chairs: Boris Vauzeilles, Francesco Nicotra

16.00 - 16.45 PL7 - Matthew Disney
Sequence-Based Design of Small Molecules that Target RNA Structure
16.45 - 17.30 PL8 - Ben Davis
Sugars & proteins: post-translational editing
17.30 - 18.00
Closing Remarks, presentation of ISBOC 2028
20.00 Social Dinner
Osteria del Treno, Via San Gregorio 46, Milano

Organizers

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